Detalhe da pesquisa
1.
Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer.
Nature
; 578(7794): 306-310, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31969702
2.
Imidazo[2,1-b]thiazoles: multitargeted inhibitors of both the insulin-like growth factor receptor and members of the epidermal growth factor family of receptor tyrosine kinases.
Bioorg Med Chem Lett
; 20(8): 2452-5, 2010 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20346655
3.
Development of multitargeted inhibitors of both the insulin-like growth factor receptor (IGF-IR) and members of the epidermal growth factor family of receptor tyrosine kinases.
Bioorg Med Chem Lett
; 19(6): 1718-21, 2009 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19217287
4.
Total Synthesis of Mycolactones A and B.
Tetrahedron
; 63(26): 5739-5753, 2007 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-17940589
5.
Preclinical Characterization of BET Family Bromodomain Inhibitor ABBV-075 Suggests Combination Therapeutic Strategies.
Cancer Res
; 77(11): 2976-2989, 2017 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28416490
6.
Discovery and optimization of anthranilic acid sulfonamides as inhibitors of methionine aminopeptidase-2: a structural basis for the reduction of albumin binding.
J Med Chem
; 49(13): 3832-49, 2006 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-16789740
7.
Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivity.
J Med Chem
; 58(5): 2180-94, 2015 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25679114
8.
Total synthesis of the mycolactones.
Org Lett
; 4(4): 647-50, 2002 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-11843613
9.
Transition-State Mimetics for HIV Protease Inhibitors: Stereocontrolled Synthesis of Hydroxyethylene and Hydroxyethylamine Isosteres by Ester-Derived Titanium Enolate Syn and Anti-Aldol Reactions.
J Org Chem
; 63(18): 6146-6152, 1998 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-11672244
10.
ESTER DERIVED TITANIUM ENOLATE ALDOL REACTION: HIGHLY DIASTEREOSELECTIVE SYNTHESIS OF SYN- AND ANTI-ALDOLS.
Tetrahedron Lett
; 38(41): 7171-7174, 1997 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30407471
11.
Correction to Structure-Guided Design of a Series of MCL-1 Inhibitors with High Affinity and Selectivity.
J Med Chem
; 58(9): 4089, 2015 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25933255
12.
Asymmetric Aldol Route to Hydroxyethylamine Isostere: Stereoselective Synthesis of the Core Unit of Saquinavir.
J Org Chem
; 62(17): 6080-6082, 1997 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30504991
13.
Insulin-like growth factor-1 receptor and ErbB kinase inhibitor combinations block proliferation and induce apoptosis through cyclin D1 reduction and Bax activation.
J Biol Chem
; 283(35): 23721-30, 2008 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-18559346
14.
Development of sulfonamide compounds as potent methionine aminopeptidase type II inhibitors with antiproliferative properties.
Bioorg Med Chem Lett
; 16(13): 3574-7, 2006 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16632353
15.
cis-1-Aminoindan-2-ol in Asymmetric Syntheses.
Synthesis (Stuttg)
; 1998(7): 937-961, 1998 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-30393403